If you’ve picked up a magazine, scrolled through social media, or chatted with a friend lately, chances are you’ve heard about GLP-1 medications. Originally developed for type 2 diabetes, GLP-1 receptor agonists have quickly become known for their role in weight management. But what many don’t realize is that these groundbreaking medications may also offer far-reaching benefits for overall health, beyond the scale.
Here at NicholsMD, we stay at the forefront of innovations that impact both metabolic health and long-term longevity, so let’s explore where the science is heading.
Studies show GLP-1s help lower blood pressure, improve cholesterol and triglycerides, and reduce overall cardiovascular risk. These changes aren’t only tied to weight loss – they may directly support healthier arteries and reduced heart disease progression.
GLP-1s improve insulin sensitivity and help regulate blood sugar, even in patients without diabetes. Exciting research shows benefits for non-alcoholic fatty liver disease (NAFLD) – slowing progression and potentially preventing cirrhosis.
One of the most fascinating areas of research is how GLP-1s may protect the brain. Early studies suggest they could help slow the onset or progression of Parkinson’s and Alzheimer’s disease. These medications also change the way patients think about food, reducing food addiction behaviors long-term, even after stopping treatment.
In February 2025, semaglutide earned FDA approval for protecting kidney function and slowing the progression of chronic kidney disease, potentially reducing the need for dialysis.
GLP-1s act as anti-inflammatories in the gut, improving the microbiome and showing promise for conditions like IBS and Crohn’s disease.
Research now shows GLP-1s may reduce cravings for alcohol and potentially aid in recovery from other addictions, much like how they reduce food cravings. While still in early stages, this could be a breakthrough in addiction treatment in the coming years.
From weight loss to heart health, liver function, and neurological protection, GLP-1 medications are transforming modern medicine. At NicholsMD, we’re watching this research closely because these discoveries may redefine how we support our patients in aging healthier and looking and feeling their best.
Are you interested in a Concierge Medical Weight Loss treatment plan? Schedule your consultation today for an individualized approach to helping you achieve your goals.
If you’ve ever typed “how to shrink pores” or “best treatment for large pores” into Google, you’re not alone –pores are one of the most searched skincare concerns online. At NicholsMD of Greenwich, we see patients daily who want smoother, clearer skin and fewer visible pores. The truth is: pores are completely normal – they’re simply the tiny openings of our hair follicles. But while you can’t eliminate pores, you can absolutely make them appear smaller and refine your skin’s texture.
When we’re young, collagen keeps the skin firm and the pores tight. As we age, collagen breaks down, which makes pores appear bigger. Other factors like excess oil production, acne, and even scarring can also make pores look more pronounced.
It’s important to remember that pores are part of healthy skin. The goal isn’t pore elimination (which isn’t possible), but rather achieving a smoother, more refined look with the right treatments and skincare routine.
Dr. Kim Nichols recommends following the “Three C’s” approach for smaller-looking pores:
Keeping pores clean prevents buildup that can stretch them out.
Boosting skin renewal helps pores stay clear and smooth. Look for skincare ingredients like:
These active ingredients improve cell turnover, tighten the pore lining, and even stimulate collagen production.
Since collagen loss makes pores more visible, boosting it is key. Treatments that trigger collagen include:
Pairing these with daily sunscreen is non-negotiable—sun protection helps prevent collagen breakdown and keeps skin firm.
Large pores are a common skin concern, but with the right skincare routine, in-office treatments, and collagen support, you can achieve smoother, more refined-looking skin. At NicholsMD of Greenwich, we specialize incustomized facials, collagen-stimulating treatments, and advanced skincare plans to minimize pores and maximize your glow.
Ready for pore-perfect skin? Book a consultation today and let our team design a treatment plan tailored to you.
Hormone Replacement Therapy (HRT) is one of the most powerful tools we have to help both women and men feel and look their best as they age. Yet, despite its many proven benefits, HRT is still surrounded by misinformation and outdated fears.
Let’s break down the most common myths about HRT and uncover the truth.
HRT refers to hormone replacement therapy, which may include estrogen, testosterone, or both. While most people associate HRT with women, it’s important to know that men benefit from it too – though in men we refer to the treatment as testosterone replacement therapy (or TRT).
For women, replacing testosterone in addition to estrogen can be critical. Testosterone supports energy, mood, mental clarity, and libido, which often decline during perimenopause and menopause. For men, TRT offers similar benefits – improving metabolism, sexual health, mental sharpness, and overall quality of life.
This is perhaps the most dangerous myth. In the 1990s, early studies suggested a potential cancer link, but those studies were later found to be flawed. Since then, numerous high-quality clinical trials have shown the opposite:
Many patients are familiar with hormone creams, patches, or injections. While these methods can work, they often result in inconsistent dosing. For example, creams can wash off, and varying absorption rates can lead to mood swings or unwanted side effects.
At NicholsMD, we offer bioidentical pellet therapy – where tiny pellets (about the size of Tic Tacs) are inserted under the skin. This method provides a steady, consistent release of hormones for 4–6 months at a time. No daily applications, no fluctuations – just consistent benefits with a simple in-office procedure.
The reality is quite the opposite. Testosterone therapy in particular supports:
Together, these effects help many patients maintain or even lose weight, while also improving body composition and overall vitality.
Not at all. While many patients love how they feel on hormone replacement therapy and choose to continue, it’s not a lifetime commitment. The best place to start is with a consultation, lab testing, and an individualized treatment plan.
At NicholsMD, most of our patients report feeling so much better on HRT that they’re eager for their next appointment – not because they “have” to continue, but because the improvements in mood, energy, and health are undeniable.
Hormone Replacement Therapy, when guided by a qualified medical team, is safe, effective, and life-changing. It’s not just about easing symptoms of aging—it’s about restoring vitality, improving overall health, and helping you feel like yourself again.
If you’re curious about whether HRT is right for you, schedule a consultation with our team. We’ll review your labs with a vitality panel, discuss your symptoms, and create a personalized plan to help you look and feel your absolute best.
Dermatologists recommend these hydrators with a hint of tint.
