If you’ve spent any time researching anti-aging skincare lately, you’ve probably come across one word over and over again: exosomes.
They’re being called the future of regenerative skincare, with claims that they can improve wrinkles, boost collagen, speed healing, and even help skin behave more like it did years ago.
So…do exosomes really work?
YES! When formulated correctly and backed by science, exosome technology represents one of the most exciting advances we’ve seen in dermatology in decades.
At NicholsMD, we’re committed to bringing our patients treatments and skincare that are supported by clinical evidence, not trends. That’s exactly why we chose to offer the complete line of plated™ Skin Science products, including plated™ INTENSE, plated™ Eye Serum, plated™ CALM, and the new plated™ BODY.
Let’s take a closer look at what exosomes actually are and why dermatologists are so excited about them.
What Are Exosomes?
Your body is constantly communicating with itself.
Every day, your cells send tiny biological “messages” to neighboring cells, telling them when to repair damage, reduce inflammation, or produce more collagen.
One of the ways they communicate is through microscopic extracellular vesicles, commonly referred to as exosomes.
Think of them as tiny delivery vehicles carrying important instructions from one cell to another.
These messages may contain:
- Growth factors
- Proteins
- Lipids
- Peptides
- RNA signaling molecules
Instead of forcing your skin to change, they help support your skin’s own natural repair processes.
That’s a very different philosophy than simply masking wrinkles or temporarily plumping the skin.
Do Exosomes Really Work?
The evidence continues to grow.
Clinical studies have shown that exosome-based skincare can help improve:
- Fine lines and wrinkles
- Skin texture
- Firmness
- Elasticity
- Hydration
- Redness
- Overall skin quality
Researchers have also found that regenerative signaling may support collagen production while helping skin recover more efficiently following procedures such as:
- Microneedling
- Fractional laser resurfacing
- Radiofrequency microneedling
- Chemical peels
For patients investing in in-office treatments, exosome skincare can be an excellent complement to help support healthier-looking skin between visits.
Why Dermatologists Are So Excited About Regenerative Skincare
Traditional anti-aging products often focus on one symptom.
- Hydration
- Pigmentation
- Wrinkles
- Texture
Regenerative skincare takes a broader approach.
Instead of simply treating visible concerns, it helps create an environment where healthier skin can thrive by supporting your skin’s own repair mechanisms.
That’s why many dermatologists believe regenerative technologies represent the next generation of skincare.
Why NicholsMD Chose plated™ Skin Science
At NicholsMD, we evaluate every product through one lens:
Would we recommend this to our own family?
plated™ Skin Science stood out because it combines sophisticated regenerative science with elegant formulations that fit easily into everyday routines.
Rather than relying on marketing buzzwords, plated™ utilizes proprietary Renewosome™ technology, featuring platelet-derived extracellular vesicles designed to support healthier-looking skin.
Because platelets naturally play a central role in tissue repair throughout the body, researchers have spent years exploring how these regenerative signals may benefit skin health when delivered topically.
The result is skincare designed to help improve overall skin quality while supporting smoother, healthier-looking skin over time.
Meet the plated™ Collection
plated™ INTENSE
INTENSE offers a higher concentration of regenerative extracellular vesicles for patients looking to target more advanced signs of aging.
We frequently recommend it following treatments like:
- Microneedling
- Fraxel® laser
- RF Microneedling
- Laser resurfacing
Patients love incorporating INTENSE into their recovery routine because it complements the skin’s natural healing process while supporting beautiful long-term results.
plated™ Eye Serum
The delicate skin around your eyes is often one of the first places to show signs of aging.
plated™ Eye Serum was specifically developed to improve the appearance of:
- Crow’s feet
- Fine lines
- Puffiness
- Crepey skin
- Under-eye texture
plated™ CALM
Healthy skin starts with a healthy skin barrier.
CALM is designed to help soothe visible redness while supporting skin recovery after procedures or during periods of irritation.
It’s particularly helpful for patients with sensitive skin or those recovering after aesthetic treatments.
NEW: plated™ BODY
One of the newest additions to the plated™ family may also be one of the most exciting.
We spend so much time caring for our face that we often forget our body loses collagen too.
As collagen naturally declines with age, the skin on the neck, chest, arms, abdomen, hands, knees, and legs can become thinner, rougher, and more crepey.
plated™ BODY extends regenerative skincare beyond the face by helping improve:
- Crepey skin
- Rough texture
- Dryness
- Loss of firmness
- Overall skin quality
It’s quickly becoming one of our favorite recommendations for patients who want comprehensive skin rejuvenation from head to toe.
Who Should Consider Exosome Skincare?
Exosome skincare is appropriate for nearly every age and skin type.
You may be an excellent candidate if you:
- Want healthier-looking skin without downtime
- Have invested in laser or microneedling treatments
- Want to support collagen production
- Are noticing early signs of aging
- Want medical-grade skincare backed by science
- Simply want your skin to function at its healthiest
Our Approach at NicholsMD
We don’t believe one product transforms skin.
Beautiful skin is built through consistency, expert guidance, and personalized care.
That’s why we combine customized skincare with in-office treatments when appropriate, creating comprehensive plans tailored to every patient’s goals.
Whether you’re focused on prevention, correction, or maintenance, regenerative skincare has become one of our favorite tools for helping patients achieve healthier, stronger skin.
Shop the Products Featured in This Blog
If you’re ready to experience regenerative skincare for yourself, our team can help determine which plated™ product is best for your skin goals.
Featured products include:
Visit our Greenwich boutique, stop by any NicholsMD location, or explore our online shop to learn more.
Frequently Asked Questions
Can exosomes replace Botox or fillers?
No. Exosome skincare works differently. While injectables relax muscles or restore volume, exosomes help support healthier skin quality and collagen production. Many patients benefit from using both as part of a comprehensive anti-aging plan.
How long does it take to see results?
Many patients notice improvements in skin texture and radiance within several weeks, while collagen remodeling and other long-term benefits develop gradually with consistent use.
Can I use exosomes after laser treatments or microneedling?
Yes. Dr. Nichols recommends regenerative skincare following procedures to help support the skin’s natural recovery process. Your provider will guide you on the appropriate timing for your specific treatment.